loading...| Preferred Name |
Graft Versus Host Disease |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3063 |
| ALT_DEFINITION |
A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following stem cell transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. A disease caused when cells from a donated stem cell graft attack the normal tissue of the transplant patient. Symptoms include jaundice, skin rash or blisters, a dry mouth, or dry eyes. |
| code |
C3063 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178115 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186316 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173231 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174019 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186341 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173217 |
| Contributing_Source |
MedDRA NICHD CTRP PCDC |
| DEFINITION |
A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following bone marrow transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation. |
| Display_Name |
Graft Versus Host Disease |
| FULL_SYN |
Graft Vs. Host Disease Runt Disease GvHD Graft vs Host Disease Graft Versus Host Disease Graft-Versus-Host-Disease GVHD graft-versus-host disease |
| Is_PCDC_ALL_Authorized_Value_For_Variable | |
| Is_PCDC_AML_Authorized_Value_For_Variable | |
| label |
Graft Versus Host Disease |
| Legacy Concept Name |
Graft_Versus_Host_Disease |
| Maps_To |
Graft versus host disease |
| Preferred_Name |
Graft Versus Host Disease |
| prefixIRI |
Thesaurus:C3063 |
| prefLabel |
Graft Versus Host Disease |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C0018133 |
| subClassOf |