loading...| Preferred Name |
Danazol |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C414 |
| ALT_DEFINITION |
A synthetic hormone that belongs to the family of drugs called androgens and is used to treat endometriosis. It is being evaluated in the treatment of endometrial cancer. |
| CAS_Registry |
17230-88-5 |
| CHEBI_ID |
CHEBI:4315 |
| Chemical_Formula |
C22H27NO2 |
| code |
C414 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle-stimulating hormone and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby exhibiting antiestrogenic, anabolic and weakly androgenic effects. (NCI04) |
| Display_Name |
Danazol |
| FDA_UNII_Code |
N29QWW3BUO |
| FULL_SYN |
Winobanin (17Alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol Danoval Cyclomen Bonzol Chronogyn danazol Danocrine Win 17757 Danol Win-17757 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol Danazol DAN DANAZOL Ladogal 17Alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole |
| label |
Danazol |
| Legacy Concept Name |
Danazol |
| NCI_Drug_Dictionary_ID |
39204 |
| NSC Number |
270916 |
| PDQ_Closed_Trial_Search_ID |
39204 |
| PDQ_Open_Trial_Search_ID |
39204 |
| Preferred_Name |
Danazol |
| prefixIRI |
Thesaurus:C414 |
| prefLabel |
Danazol |
| Semantic_Type |
Pharmacologic Substance Organic Chemical |
| UMLS_CUI |
C0010961 |
| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2092 |