loading...| Preferred Name |
Mantle Cell Lymphoma |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4337 |
| ALT_DEFINITION |
An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that usually occurs in middle-aged or older adults. It is marked by small- to medium-size cancer cells that may be in the lymph nodes, spleen, bone marrow, blood, and gastrointestinal system. |
| code |
C4337 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193248 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168661 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193231 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193006 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168657 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103133 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193175 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193249 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168662 |
| Contributing_Source |
CPTAC mCode CTEP CTRP GDC Cellosaurus |
| DEFINITION |
A non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA. |
| Display_Name |
Mantle Cell Lymphoma |
| FULL_SYN |
Mantle Zone Lymphoma Mantle zone lymphoma Classical Mantle Cell Lymphoma Mantle cell lymphoma Mantle cell lymphoma, unspecified site Mantle Cell Lymphoma MCL mantle cell lymphoma |
| ICD-O-3_Code |
9673/3 |
| Is_Value_For_GDC_Property | |
| label |
Mantle Cell Lymphoma |
| Legacy Concept Name |
Mantle_Cell_Lymphoma |
| Maps_To |
Mantle zone lymphoma Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Mantle cell lymphoma Mantle cell lymphoma, unspecified site, extranodal and solid organ sites Mantle cell lymphoma, unspecified site Mantle cell lymphoma, lymph nodes of multiple sites Mantle cell lymphoma (Includes all variants blastic, pleomorphic, small cell) 9673/3 Mantle cell lymphoma, extranodal and solid organ sites |
| Neoplastic_Status |
Malignant |
| Preferred_Name |
Mantle Cell Lymphoma |
| prefixIRI |
Thesaurus:C4337 |
| prefLabel |
Mantle Cell Lymphoma |
| Semantic_Type |
Neoplastic Process |
| UMLS_CUI |
C0334634 |
| subClassOf |