loading...| Preferred Name |
Ofloxacin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C712 |
| Accepted_Therapeutic_Use_For |
Various bacterial infections |
| ALT_DEFINITION |
An antibiotic drug used to treat infection. It belongs to the family of drugs called quinolone antibiotics. |
| CAS_Registry |
83380-47-6 82419-36-1 |
| CHEBI_ID |
CHEBI:7731 |
| Chemical_Formula |
C18H20FN3O4 |
| code |
C712 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04) |
| FDA_UNII_Code |
A4P49JAZ9H |
| FULL_SYN |
Ocuflox ofloxacin HOE 280 9-Fluoro-2,3-Dihydro-3-Methyl-10-(4-Methyl-1-Piperazinyl)-7-Oxo-7H-Pyrido(1,2,3-de)(1,4)benzoxazine-6-Carboxylic Acid, DL- Floxin DL-8280 OFLOXACIN Ofloxacin |
| label |
Ofloxacin |
| Legacy Concept Name |
Ofloxacin |
| NCI_Drug_Dictionary_ID |
42865 |
| NSC Number |
727071 |
| PDQ_Closed_Trial_Search_ID |
42865 |
| PDQ_Open_Trial_Search_ID |
42865 |
| Preferred_Name |
Ofloxacin |
| prefixIRI |
Thesaurus:C712 |
| prefLabel |
Ofloxacin |
| Semantic_Type |
Pharmacologic Substance Organic Chemical Antibiotic |
| UMLS_CUI |
C0028902 |
| subClassOf |