| Preferred Name |
sclerotome |
| Synonyms |
sclerotomes sclerotomus |
| Definitions |
Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0003089 |
| database_cross_reference |
TAO:0001080 AAO:0010571 FMA:295652 AEO:0000212 EMAPA:31159 EHDAA2:0003439 ZFA:0001080 UMLS:C0183176 VHOG:0000680 XAO:0000397 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34287 |
| depicted_by |
http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png |
| develops_from | |
| external_definition |
Skeletogenic portion of somites.[AAO] |
| external_ontology_notes |
part_of somite in XAO |
| has_exact_synonym |
sclerotomes |
| has_obo_namespace |
uberon |
| has_related_synonym |
sclerotomus |
| homology_notes |
The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] |
| id |
UBERON:0003089 |
| imported from | |
| in_subset |
http://purl.obolibrary.org/obo/uberon#vertebrate_core http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#pheno_slim |
| label |
sclerotome |
| notation |
UBERON:0003089 |
| prefLabel |
sclerotome |
| textual definition |
Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. |
| treeView | |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0007530 |