loading...| Preferred Name |
pharyngeal pouch |
| Synonyms |
branchial pouch visceral pouches pharyngeal pouches visceral pouch |
| Definitions |
An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. The pouches are polarized structures. For example, whereas the rostral half of each pouch expresses Bmp-7, the caudal half expresses FGF-8 and the dorsal aspect of each pouch is marked via its expression of Pax-1. each pouch has an individual sense of identity. Shh expression is a prominent early feature of the caudal endoderm of the second arch, and individual pouches mark the anterior limits of expression of Hox genes within the pharyngeal endoderm; Hox-a2 has a rostral boundary at the second pouch, Hox-a3 at the third pouch and Hox-a4 at the most caudal pouch[PMID:16313389] |
| ID |
http://purl.obolibrary.org/obo/UBERON_0004117 |
| comment |
The pouches are polarized structures. For example, whereas the rostral half of each pouch expresses Bmp-7, the caudal half expresses FGF-8 and the dorsal aspect of each pouch is marked via its expression of Pax-1. each pouch has an individual sense of identity. Shh expression is a prominent early feature of the caudal endoderm of the second arch, and individual pouches mark the anterior limits of expression of Hox genes within the pharyngeal endoderm; Hox-a2 has a rostral boundary at the second pouch, Hox-a3 at the third pouch and Hox-a4 at the most caudal pouch[PMID:16313389] |
| database_cross_reference |
EMAPA:32752 TAO:0001106 FMA:293063 XAO:0000282 EHDAA:1086 AAO:0011113 EHDAA:617 EFO:0003627 VHOG:0001203 ZFA:0001106 UMLS:C0231067 EHDAA:579 EHDAA:1669 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34252 http://linkedlifedata.com/resource/umls/id/C0231067 |
| develops_from | |
| external_definition |
Outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits. Crump et al, 2004.[TAO] |
| external_ontology_notes |
EMAPA also includes a distinct pouch endoderm |
| has exact synonym |
branchial pouch visceral pouch |
| has_obo_namespace |
uberon |
| has_related_synonym |
visceral pouches pharyngeal pouches |
| homology_notes |
A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG] |
| id |
UBERON:0004117 |
| imported from | |
| in_subset |
http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core http://purl.oboInOwllibrary.org/oboInOwl/uberon#vertebrate_core http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim |
| label |
pharyngeal pouch |
| notation |
UBERON:0004117 |
| part_of | |
| prefLabel |
pharyngeal pouch |
| textual definition |
An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. |
| treeView |
http://purl.obolibrary.org/obo/UBERON_0000922 |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0005291 |