loading...| Preferred Name |
JUVENILE MYELOMONOCYTIC LEUKEMIA |
| Synonyms |
LEUKEMIA, CHRONIC MYELOMONOCYTIC |
| ID |
http://purl.bioontology.org/ontology/OMIM/607785 |
| altLabel |
LEUKEMIA, CHRONIC MYELOMONOCYTIC JMML LEUKEMIA, JUVENILE MYELOMONOCYTIC CMML |
| cui |
C0349639 C0023480 |
| Gene Locus |
17q11.2 |
| Gene Symbol |
NFNS WSS NF1 VRNF |
| Has manifestation | |
| MIMTYPEMEANING |
Phenotype description, molecular basis known. |
| notation |
607785 |
| OMIM Entry Type |
3 |
| OMIM MimType Value |
pound |
| prefLabel |
JUVENILE MYELOMONOCYTIC LEUKEMIA |
| Scope Statement |
Caused by somatic mutation in the RHO GTPase-activating protein 26 gene (ARHGAP26, 605370.0001) [MOLECULAR BASIS] Caused by somatic mutation in the neuroblastoma Ras viral oncogene (NRAS, 164790.0003) [MOLECULAR BASIS] Caused by somatic mutation in the Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog gene (KRAS, 190070.0003) [MOLECULAR BASIS] Caused by somatic mutation in the protein tyrosine phosphatase, nonreceptor-type, 11 gene (PTPN11, 176876.0014) [MOLECULAR BASIS] One family has been reported with germline CBL mutation (last curated May 2016) [MISCELLANEOUS] Caused by mutation in the CBL gene (CBL, 165360.0009) [MOLECULAR BASIS] Caused by mutation in the NF1 gene (NF1, 613113.0019) [MOLECULAR BASIS] |
| tui |
T191 |