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loading...| Preferred Name |
DNA Methyltransferase Inhibitor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2083 |
| code |
C2083 |
| DEFINITION |
Any substance that inhibits DNA methyltransferase, an enzyme required for DNA methylation. Inhibition of DNA methyltransferase results in hypomethylation of genomic DNA and cell cycle arrest at S-phase. Hypomethylation in malignant cells may also restore suppressor gene expression and re-establish controlled growth and differentiation. |
| FULL_SYN |
DNA Methyltransferase Inhibitor DNMT Inhibitor |
| label |
DNA Methyltransferase Inhibitor |
| NCI_META_CUI |
CL1642980 |
| P366 |
DNA_Methyltransferase_Inhibitor |
| Preferred_Name |
DNA Methyltransferase Inhibitor |
| prefixIRI |
Thesaurus:C2083 |
| prefLabel |
DNA Methyltransferase Inhibitor |
| Semantic_Type |
Chemical Viewed Functionally |
| subClassOf |
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