Preferred Name

professional antigen presenting cell

Synonyms

APC

Definitions

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

ID

http://purl.obolibrary.org/obo/CL_0000145

comment

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

capable of

http://purl.obolibrary.org/obo/GO_0002504

definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

has_broad_synonym

APC

in_subset

http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim

label

professional antigen presenting cell

prefixIRI

CL:0000145

prefLabel

professional antigen presenting cell

subClassOf

http://purl.obolibrary.org/obo/CL_0000738

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http://purl.obolibrary.org/obo/CL_0000145 Uber Anatomy Ontology / 超级解剖学本体 LOOM
http://purl.obolibrary.org/obo/CL_0000145 Uber Anatomy Ontology / 超级解剖学本体 SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.obolibrary.org/obo/CL_0000145 Human Disease Ontology / 人类疾病本体 SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 Cell Ontology / 细胞本体 LOOM
http://purl.obolibrary.org/obo/CL_0000145 Cell Ontology / 细胞本体 SAME_URI