Preferred Name

ovarian follicle

Synonyms

ovary follicle

folliculi ovarici primarii

egg follicle

follicle of ovary viewed macroscopically

follicle of ovary

folliculi ovarici vesiculosi

Definitions

A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified].

ID

http://purl.obolibrary.org/obo/UBERON_0001305

database_cross_reference

MAT:0000449

UMLS:C0018120

MA:0001707

GAID:371

Wikipedia:Ovarian_follicle

NCIT:C33244

CALOHA:TS-0726

VHOG:0001536

BTO:0000475

EMAPA:35627

TAO:0001110

SCTID:361111009

FMA:18640

ZFA:0001110

MESH:D006080

definition

A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified].

depicted by

http://upload.wikimedia.org/wikipedia/commons/c/ca/Human_ovarian_follicle.jpg

https://upload.wikimedia.org/wikipedia/commons/e/e6/Primary_follicle-4.JPG

develops_from

http://purl.obolibrary.org/obo/UBERON_0005296

editor note

TODO - align subtypes based on staging, which is taxon-specific

external_definition

Oocyte development of zebrafish has been divided into five stages based on morphological criteria and on physiological and biochemical events. Stage I follicles (less than 140 microns) are primary growth stage, stage II follicles (140-340 microns) are cortical alveolus stage, stage III (340-690 microns) are vitellogenesis, stage IV (690-730 microns) are oocyte maturation, and stage V follicles are matured egg. Selman et al, 1993.[TAO]

function_notes

The somatic cell component of the follicle produces hormones important for oocyte development and proper endocrine function

has exact synonym

ovary follicle

follicle of ovary viewed macroscopically

follicle of ovary

has part

http://purl.obolibrary.org/obo/CL_0000023

http://purl.obolibrary.org/obo/UBERON_0000038

http://purl.obolibrary.org/obo/CL_0002174

has related synonym

folliculi ovarici primarii

egg follicle

folliculi ovarici vesiculosi

has_obo_namespace

uberon

homology_notes

Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]

id

UBERON:0001305

in_subset

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

label

ovarian follicle

notation

UBERON:0001305

prefLabel

ovarian follicle

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

taxon_notes

These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. These eggs/ova are only developed once every menstrual cycle (e.g. once a month in humans)

treeView

http://purl.obolibrary.org/obo/UBERON_0005296

subClassOf

http://purl.obolibrary.org/obo/PR_000050567

http://purl.obolibrary.org/obo/UBERON_0004120

http://purl.obolibrary.org/obo/UBERON_8450001

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0001305 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/UBERON_0001305 中国人类表型本体 / Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001305 Cell Ontology / 细胞本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0001305 Cell Ontology / 细胞本体 SAME_URI
http://purl.bioontology.org/ontology/MESH/D006080 Medical Subject Headings / 医学主题词表 LOOM
http://purl.obolibrary.org/obo/BTO_0000475 BRENDA Tissue and Enzyme Source Ontology / 布兰达组织和酶源本体 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33244 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM