Preferred Name |
Moxalactam |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C670 |
CAS_Registry |
64952-97-2 |
CHEBI_ID |
CHEBI:599928 |
Chemical_Formula |
C20H20N6O9S |
code |
C670 |
Concept_In_Subset | |
Contributing_Source |
FDA |
DEFINITION |
A semisynthetic oxa-beta-lactam antibiotic, with antibacterial activity used mainly against gram-negative aerobic bacteria. Replacing the beta-lactam sulfur atom for an oxygen atom and the presence of the methyltetrazolethio moiety and the para-hydroxyphenylmalonyl group, increases the antibacterial activity of moxalactam. The 7-alpha-methoxy group and the para-hydroxyphenylmalonyl group increases the stability of this agent against beta-lactamases. The use of this agent has been associated with fatal bleeding events. |
FDA_UNII_Code |
VUF6C936Z3 |
FULL_SYN |
Ly 127935 MOXALACTAM Moxalactam Moxam Latamoxef |
Has_Salt_Form | |
label |
Moxalactam |
Legacy Concept Name |
Moxalactam |
NCI_Drug_Dictionary_ID |
39507 |
PDQ_Closed_Trial_Search_ID |
39507 |
PDQ_Open_Trial_Search_ID |
39507 |
Preferred_Name |
Moxalactam |
prefixIRI |
Thesaurus:C670 |
prefLabel |
Moxalactam |
Semantic_Type |
Pharmacologic Substance Organic Chemical Antibiotic |
UMLS_CUI |
C0026651 |
subClassOf |