loading...| Preferred Name |
ofloxacin |
| Synonyms |
HOE 280 ofloxacino OFLX Prifloxin ofloxacin Ocuflox Visiren Gailuoxian DL 8280 rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid ofloxacinum Exocin (+-)-ofloxacin HOE-280 Tarivid ORF 18489 ofloxacine Oxaldin Prifloxcin (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid rac-ofloxacin racemic ofloxacin Floxin DL-8280 |
| Definitions |
A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
| ID |
http://purl.obolibrary.org/obo/CHEBI_7731 |
| charge |
0 |
| database_cross_reference |
PMID:35897550 CAS:82419-36-1 PMID:11710934 VSDB:1898 PMID:36004580 MetaCyc:CPD-12843 PMID:24497308 DrugBank:DB01165 PMID:3546152 PMID:1804789 PMID:9228220 Wikipedia:Ofloxacin PMID:16669862 PMID:19646516 PMID:6960805 PMID:36268299 KEGG:C07321 KEGG:D00453 PMID:3469159 PMID:24550337 PMID:7884650 PMID:36228398 PMID:11903499 PMID:15008519 PMID:15557076 LINCS:LSM-4370 Drug_Central:1981 HMDB:HMDB0015296 Reaxys:3657947 PMID:12827054 |
| definition |
A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
| formula |
C18H20FN3O4 |
| has part | |
| has role |
http://purl.obolibrary.org/obo/CHEBI_36047 http://purl.obolibrary.org/obo/CHEBI_53559 http://purl.obolibrary.org/obo/CHEBI_50750 |
| has_alternative_id |
CHEBI:100146 |
| has_exact_synonym |
rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| has_obo_namespace |
chebi_ontology |
| has_related_synonym |
HOE 280 ofloxacino OFLX Prifloxin ofloxacin Ocuflox Visiren Gailuoxian DL 8280 rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid ofloxacinum Exocin (+-)-ofloxacin HOE-280 Tarivid ORF 18489 ofloxacine Oxaldin Prifloxcin (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid rac-ofloxacin racemic ofloxacin Floxin DL-8280 |
| id |
CHEBI:7731 |
| in_subset | |
| label |
ofloxacin |
| mass |
361.373 |
| monoisotopicmass |
361.14378 |
| notation |
CHEBI:7731 |
| prefLabel |
ofloxacin |
| treeView |
http://purl.obolibrary.org/obo/CHEBI_60911 |
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_60911 |