Mondo Disease Ontology / Mondo疾病本体

Last uploaded: August 7, 2023
Preferred Name

leukemia

Synonyms

leukemias, general

leukemia (disease)

leukemia, disease

blood (leukemia)

leukemia

leukemias

leukemia, malignant

Definitions

A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

ID

http://purl.obolibrary.org/obo/MONDO_0005059

database_cross_reference

ICD9:208.90

UMLS:C0023418

ICD9:207.8

HP:0001909

ICD9:207.80

ICD9:208

ICD9:208.8

DOID:1240

MESH:D007938

SCTID:93143009

EFO:0000565

ICDO:9800/3

ICD9:208.80

ICD9:207

NCIT:C3161

ICD9:208.9

definition

A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

exactMatch

http://identifiers.org/mesh/D007938

http://identifiers.org/snomedct/93143009

http://linkedlifedata.com/resource/umls/id/C0023418

http://purl.obolibrary.org/obo/DOID_1240

http://purl.obolibrary.org/obo/NCIT_C3161

has_exact_synonym

leukemias, general

leukemia (disease)

leukemia, disease

blood (leukemia)

leukemia

leukemias

leukemia, malignant

IAO_0000589

leukemia (disease)

id

MONDO:0005059

label

leukemia

notation

MONDO:0005059

prefLabel

leukemia

treeView

http://purl.obolibrary.org/obo/MONDO_0044881

subClassOf

http://purl.obolibrary.org/obo/MONDO_0044881

excluded subClassOf

http://purl.obolibrary.org/obo/MONDO_0005157

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http://purl.bioontology.org/ontology/MESH/D007938 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU008966 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bioontology.org/ontology/LNC/LA10545-4 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://www.ebi.ac.uk/efo/EFO_0000565 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/DOID_1240 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/DOID_1240 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_1240 Ontology of Drug Adverse Events / 药物不良反应本体 LOOM
http://purl.obolibrary.org/obo/DOID_1240 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) / 国家实验细胞资源共享服务平台(NICR)细胞系本体子集 LOOM
http://purl.obolibrary.org/obo/DOID_1240 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.obolibrary.org/obo/HP_0001909 Human Phenotype Ontology / 人类表型本体 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3161 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023418 MedlinePlus Health Topics / MedlinePlus网站健康主题 LOOM