Preferred Name

Mucocutaneous Lymph Node Syndrome

Synonyms

Mucocutaneous lymph node syndrome

Definitions

<h3>What is Kawasaki disease?</h3> <p>Kawasaki disease is a rare illness that usually affects small children. Other names for it are Kawasaki syndrome and mucocutaneous lymph node syndrome. It is a type of <a href="https://medlineplus.gov/vasculitis.html">vasculitis</a>, which is inflammation of the blood vessels. Kawasaki disease is serious, but most children can fully recover if they are treated right away.</p> <h3>What causes Kawasaki disease?</h3> <p>Kawasaki disease happens when the immune system injures the blood vessels by mistake. Researchers do not fully know why this happens. But when it does, the blood vessels become inflamed and can narrow or close off.</p> <p>Genetics may play a role in Kawasaki disease. There may also be environmental factors, such as infections. It does not seem to be contagious. This means that it cannot be passed from one child to another.</p> <h3>Who is at risk for Kawasaki disease?</h3> <p>Kawasaki disease usually affects children under the age of 5. But older children and adults can sometimes get it. It is more common in boys than girls. It can affect children of any race, but those with Asian or Pacific Islander descent are more likely to get it.</p> <h3>What are the symptoms of Kawasaki disease?</h3> <p>The symptoms of Kawasaki disease may include:</p><ul> <li>High <a href="https://medlineplus.gov/fever.html">fever</a> lasting at least five days</li> <li>A <a href="https://medlineplus.gov/rashes.html">rash</a>, often on the back, chest, and groin</li> <li>Swollen hands and feet</li> <li>Redness of the lips, lining of the mouth, tongue, palms of the hand, and soles of the feet</li> <li><a href="https://medlineplus.gov/pinkeye.html">Pink eye</a></li> <li>Swollen lymph nodes</li> </ul> <h3>What other problems can Kawasaki disease cause?</h3> <p>Sometimes Kawasaki disease can affect the walls of the coronary arteries. These arteries bring supply blood and oxygen to your heart. This can lead to:</p><ul> <li>An <a href="https://medlineplus.gov/aneurysms.html">aneurysm</a> (bulging and thinning of the walls of the arteries). This can raise the risk of <a href="https://medlineplus.gov/bloodclots.html">blood clots</a>s in the arteries. If the blood clots are not treated, they could lead to a <a href="https://medlineplus.gov/heartattack.html">heart attack</a> or internal bleeding.</li> <li>Inflammation in the heart</li> <li><a href="https://medlineplus.gov/heartvalvediseases.html">Heart valve problems</a></li> </ul> <p>Kawasaki disease can also affect other parts of the body, including the brain and nervous system, the immune system, and the digestive system.</p> <h3>How is Kawasaki disease diagnosed?</h3> <p>There is no specific test for Kawasaki disease. To make a diagnosis, your child's health care provider may use many tools:</p><ul> <li>A physical exam, which includes looking at the signs and symptoms</li> <li>Blood and urine tests to rule out other diseases and check for signs of inflammation</li> <li><a href="https://medlineplus.gov/hearthealthtests.html">Tests</a> to check for damage to the heart, such as an echocardiogram and <a href="https://medlineplus.gov/lab-tests/electrocardiogram/">electrocardiogram</a> (EKG)</li> </ul> <h3>What are the treatments for Kawasaki disease?</h3> <p>Kawasaki disease is usually treated in the hospital with an intravenous (IV) dose of immunoglobulin (IVIG). Aspirin may also be part of the treatment. But do not give your child aspirin unless the health care provider tells you to. Aspirin can cause <a href="https://medlineplus.gov/reyesyndrome.html">Reye syndrome</a> in children. This is a rare, serious illness that can affect the brain and liver.</p> <p>Usually treatment works. But if it is not working well enough, the provider may also give your child other medicines to fight the inflammation. If the disease affects your child's heart, he or she might need additional medicines, surgery, or other medical procedures.</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026691

altLabel

Mucocutaneous lymph node syndrome

Kawasaki Disease

cui

C0026691

Date created

02/11/2009

definition

What is Kawasaki disease?

Kawasaki disease is a rare illness that usually affects small children. Other names for it are Kawasaki syndrome and mucocutaneous lymph node syndrome. It is a type of vasculitis, which is inflammation of the blood vessels. Kawasaki disease is serious, but most children can fully recover if they are treated right away.

What causes Kawasaki disease?

Kawasaki disease happens when the immune system injures the blood vessels by mistake. Researchers do not fully know why this happens. But when it does, the blood vessels become inflamed and can narrow or close off.

Genetics may play a role in Kawasaki disease. There may also be environmental factors, such as infections. It does not seem to be contagious. This means that it cannot be passed from one child to another.

Who is at risk for Kawasaki disease?

Kawasaki disease usually affects children under the age of 5. But older children and adults can sometimes get it. It is more common in boys than girls. It can affect children of any race, but those with Asian or Pacific Islander descent are more likely to get it.

What are the symptoms of Kawasaki disease?

The symptoms of Kawasaki disease may include:

  • High fever lasting at least five days
  • A rash, often on the back, chest, and groin
  • Swollen hands and feet
  • Redness of the lips, lining of the mouth, tongue, palms of the hand, and soles of the feet
  • Pink eye
  • Swollen lymph nodes

What other problems can Kawasaki disease cause?

Sometimes Kawasaki disease can affect the walls of the coronary arteries. These arteries bring supply blood and oxygen to your heart. This can lead to:

  • An aneurysm (bulging and thinning of the walls of the arteries). This can raise the risk of blood clotss in the arteries. If the blood clots are not treated, they could lead to a heart attack or internal bleeding.
  • Inflammation in the heart
  • Heart valve problems

Kawasaki disease can also affect other parts of the body, including the brain and nervous system, the immune system, and the digestive system.

How is Kawasaki disease diagnosed?

There is no specific test for Kawasaki disease. To make a diagnosis, your child's health care provider may use many tools:

  • A physical exam, which includes looking at the signs and symptoms
  • Blood and urine tests to rule out other diseases and check for signs of inflammation
  • Tests to check for damage to the heart, such as an echocardiogram and electrocardiogram (EKG)

What are the treatments for Kawasaki disease?

Kawasaki disease is usually treated in the hospital with an intravenous (IV) dose of immunoglobulin (IVIG). Aspirin may also be part of the treatment. But do not give your child aspirin unless the health care provider tells you to. Aspirin can cause Reye syndrome in children. This is a rare, serious illness that can affect the brain and liver.

Usually treatment works. But if it is not working well enough, the provider may also give your child other medicines to fight the inflammation. If the disease affects your child's heart, he or she might need additional medicines, surgery, or other medical procedures.

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026691

Inverse of SY

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026691

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026691

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026691

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/kawasakidisease.html

MP PRIMARY INSTITUTE URL

National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/

notation

C0026691

prefLabel

Mucocutaneous Lymph Node Syndrome

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0042384

Scope Statement

Kawasaki disease is a rare childhood disease that makes the walls of the blood vessels in the body become inflamed. Learn what symptoms to look for. https://medlineplus.gov/kawasakidisease.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C2362499

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456601

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020962

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/611775 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/ICD10CM/M30.3 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI
http://www.ebi.ac.uk/efo/EFO_0004246 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.bioontology.org/ontology/MESH/D009080 Medical Subject Headings / 医学主题词表 CUI
http://purl.bioontology.org/ontology/MESH/D009080 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/ICD10/M30.3 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 CUI
http://purl.obolibrary.org/obo/MONDO_0012727 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://purl.obolibrary.org/obo/MONDO_0012727 GenEpiO / 基因组流行病学本体 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/4A44.5 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM
http://purl.bmicc.cn/ontology/ICD10CN/M30.3 《国际疾病分类》第10版中文版 / International Classification of Diseases, 10th Edition, China CUI