loading...| Preferred Name |
Sulbactam |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61957 |
| CAS_Registry |
68373-14-8 |
| CHEBI_ID |
CHEBI:9321 |
| Chemical_Formula |
C8H11NO5S |
| code |
C61957 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity. |
| FDA_UNII_Code |
S4TF6I2330 |
| FULL_SYN |
CP 45899 SULBACTAM Sulbactam (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide |
| Has_Salt_Form | |
| label |
Sulbactam |
| Legacy Concept Name |
Sulbactam |
| Preferred_Name |
Sulbactam |
| prefixIRI |
Thesaurus:C61957 |
| prefLabel |
Sulbactam |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0038665 |
| subClassOf |