loading...| Preferred Name |
exocrine pancreas |
| Synonyms |
exocrine component of pancreas exocrine part of pancreas exocrine pancreas pars exocrina pancreatis |
| Definitions |
The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0000017 |
| capable of part of | |
| contributes to morphology of | |
| database_cross_reference |
EV:0100093 CALOHA:TS-1241 Wikipedia:Exocrine_component_of_pancreas FMA:16017 ZFA:0001249 BTO:0000434 MA:0002415 SCTID:248202004 UMLS:C0553695 TAO:0001249 AAO:0010407 VHOG:0000048 NCIT:C32546 XAO:0000137 EMAPA:35328 MESH:D046790 |
| definition |
The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. |
| develops_from | |
| has part | |
| has_exact_synonym |
exocrine pancreas pars exocrina pancreatis |
| has_obo_namespace |
uberon |
| has_related_synonym |
exocrine component of pancreas exocrine part of pancreas |
| id |
UBERON:0000017 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#organ_slim |
| label |
exocrine pancreas |
| notation |
UBERON:0000017 |
| part_of | |
| prefLabel |
exocrine pancreas |
| RO_0002175 | |
| treeView | |
| UBPROP_0000001 |
The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO] The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG] |
| UBPROP_0000003 |
In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG] |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0000409 |