loading...| Preferred Name |
type B synovial cell |
| Synonyms |
synovial fibroblast fibroblast-like synoviocyte |
| Definitions |
A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis. |
| ID |
http://purl.obolibrary.org/obo/CL_0002301 |
| comment |
Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis. |
| capable of | |
| contributor | |
| creation_date |
2010-09-13T03:39:14Z |
| database_cross_reference |
FMA:66788 BTO:0003652 |
| definition |
A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. |
| has exact synonym |
synovial fibroblast fibroblast-like synoviocyte |
| label |
type B synovial cell |
| part_of | |
| prefixIRI |
CL:0002301 |
| prefLabel |
type B synovial cell |
| produces | |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CL_0002301 | Cell Ontology / 细胞本体 | LOOM | |
| http://purl.obolibrary.org/obo/CL_0002301 | Cell Ontology / 细胞本体 | SAME_URI |