Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

tympanic membrane

Synonyms

ear drum

tympanum

eardrum

paries membranaceus cavi tympani

membranous wall of tympanic cavity

myrinx

Rivinus' membrane

lateral wall of tympanic cavity

Definitions

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

ID

http://purl.obolibrary.org/obo/UBERON_0002364

adjacent to

http://purl.obolibrary.org/obo/UBERON_0004114

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001756

database_cross_reference

EMAPA:19062

GAID:870

XAO:0000212

FMA:9595

SCTID:181180005

VHOG:0001146

MA:0000257

Wikipedia:Tympanic_membrane

MESH:D014432

UMLS:C0041445

NCIT:C12502

definition

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

develops_from

http://purl.obolibrary.org/obo/UBERON_0009213

has part

http://purl.obolibrary.org/obo/UBERON_0010069

http://purl.obolibrary.org/obo/UBERON_0010070

http://purl.obolibrary.org/obo/UBERON_0005042

has_exact_synonym

ear drum

eardrum

paries membranaceus cavi tympani

membranous wall of tympanic cavity

myrinx

Rivinus' membrane

lateral wall of tympanic cavity

has_obo_namespace

uberon

has_related_synonym

tympanum

id

UBERON:0002364

in_subset

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

label

tympanic membrane

never_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_8459

notation

UBERON:0002364

overlaps

http://purl.obolibrary.org/obo/UBERON_0001691

http://purl.obolibrary.org/obo/UBERON_0001352

part_of

http://purl.obolibrary.org/obo/UBERON_0001756

prefLabel

tympanic membrane

treeView

http://purl.obolibrary.org/obo/UBERON_0009213

http://purl.obolibrary.org/obo/UBERON_0001756

UBPROP_0000001

The thin membrane which closes externally the cavity of the middle ear and is deeply sited at the bottom of the external auditory meatus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]

UBPROP_0000003

In particular, a tympanic membrane was not present in the earliest tetrapods (...). An ear utilizing a tympanic membrane evolved independently at least three times in tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well established][VHOG]

UBPROP_0000011

The tympanic membrane (TM) has three layers, two epithelia provided by the external acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal cleft and pouch, and a mesenchymally derived fibrous stratum

UBPROP_0000012

most AOs consider this part of the middle ear, so we go with this and place it in the middle ear as a border to the external, although it could be considered to overlap the external ear in that it has an EAM layer as part - for this reason we do not consider middle and external ear to be spatially disjoint.

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000094

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12502 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 中国人类表型本体 / Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 Uber Anatomy Ontology / 超级解剖学本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 Uber Anatomy Ontology / 超级解剖学本体 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 Human Disease Ontology / 人类疾病本体 SAME_URI
http://purl.bioontology.org/ontology/MESH/D014432 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/LNC/LA9368-7 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/XA08X4 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM
http://purl.bioontology.org/ontology/LNC/MTHU014731 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://purl.org/sig/ont/fma/fma9595 Foundational Model of Anatomy / 解剖学基础模型本体 LOOM
http://purl.bioontology.org/ontology/LNC/LP7665-5 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM