loading...| Preferred Name |
progressive bulbar palsy |
| Synonyms |
progressive bulbar atrophy bulbar palsy, progressive, of childhood Fazio-Londe disease |
| Definitions |
Progressive bulbar palsy involves the brain stem. The brain stem is the part of the brain needed for swallowing, speaking, chewing, and other functions. Signs and symptoms of progressive bulbar palsy include difficulty swallowing, weak jaw and facial muscles, progressive loss of speech, and weakening of the tongue. Additional symptoms include less prominent weakness in the arms and legs, and outbursts of laughing or crying (called emotional lability). Progressive bulbar palsy is considered a variant form of amyotrophic lateral sclerosis (ALS). Many people with progressive bulbar palsy later develop ALS. While there is no cure for progressive bulbar palsy or for ALS, doctors can treat symptoms. |
| ID |
http://purl.obolibrary.org/obo/MONDO_0008890 |
| database_cross_reference |
ICD9:335.22 EFO:0003783 ICD10CM:G12.22 SCTID:54304004 DOID:681 NCIT:C85026 MESH:D010244 UMLS:C0030442 GARD:0010928 |
| definition |
Progressive bulbar palsy involves the brain stem. The brain stem is the part of the brain needed for swallowing, speaking, chewing, and other functions. Signs and symptoms of progressive bulbar palsy include difficulty swallowing, weak jaw and facial muscles, progressive loss of speech, and weakening of the tongue. Additional symptoms include less prominent weakness in the arms and legs, and outbursts of laughing or crying (called emotional lability). Progressive bulbar palsy is considered a variant form of amyotrophic lateral sclerosis (ALS). Many people with progressive bulbar palsy later develop ALS. While there is no cure for progressive bulbar palsy or for ALS, doctors can treat symptoms. |
| exactMatch |
http://identifiers.org/mesh/D010244 http://linkedlifedata.com/resource/umls/id/C0030442 http://purl.obolibrary.org/obo/DOID_681 http://purl.bioontology.org/ontology/ICD10CM/G12.22 |
| has_narrow_synonym |
bulbar palsy, progressive, of childhood Fazio-Londe disease |
| has_related_synonym |
progressive bulbar atrophy |
| IAO_0000233 | |
| id |
MONDO:0008890 |
| in_subset | |
| label |
progressive bulbar palsy |
| notation |
MONDO:0008890 |
| prefLabel |
progressive bulbar palsy |
| seeAlso |
https://rarediseases.info.nih.gov/diseases/10928/progressive-bulbar-palsy |
| treeView |
http://purl.obolibrary.org/obo/MONDO_0002782 http://purl.obolibrary.org/obo/MONDO_0008891 |
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0002782 http://purl.obolibrary.org/obo/MONDO_0008891 |