Preferred Name

Hepatoblastoma

Synonyms

Pediatric Embryonal Hepatoma

HEPATOBLASTOMA, MALIGNANT

HBL

Pediatric Hepatoblastoma

Hepatoblastoma

hepatoblastoma

Definitions

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.

ID

http://purl.obolibrary.org/obo/NCIT_C3728

definition

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.

has_exact_synonym

Pediatric Embryonal Hepatoma

HEPATOBLASTOMA, MALIGNANT

HBL

Pediatric Hepatoblastoma

Hepatoblastoma

hepatoblastoma

has_obo_namespace

mouse_pathology.ontology

id

NCIT:C3728

label

Hepatoblastoma

notation

NCIT:C3728

prefLabel

Hepatoblastoma

subClassOf

http://purl.obolibrary.org/obo/MPATH_352

http://purl.obolibrary.org/obo/NCIT_C7708

http://purl.obolibrary.org/obo/NCIT_C3264

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http://www.ebi.ac.uk/efo/EFO_1000292 Experimental Factor Ontology / 实验性因素本体 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3728 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0206624 MedlinePlus Health Topics / MedlinePlus网站健康主题 LOOM
http://www.orpha.net/ORDO/Orphanet_449 Orphanet Rare Disease Ontology / Orphanet罕见病本体 LOOM
http://purl.bioontology.org/ontology/ICD10CM/C22.2 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU007922 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.obolibrary.org/obo/HP_0002884 Human Phenotype Ontology / 人类表型本体 LOOM
http://purl.bioontology.org/ontology/MESH/D018197 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/ICD10/C22.2 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 LOOM
http://purl.obolibrary.org/obo/DOID_687 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_687 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.obolibrary.org/obo/MONDO_0018666 Mondo Disease Ontology / Mondo疾病本体 LOOM