Preferred Name

Osteonecrosis

Definitions

<p>Osteonecrosis is a disease caused by reduced blood flow to bones in the joints. In people with healthy bones, new bone is always replacing old bone. In osteonecrosis, the lack of blood causes the bone to break down faster than the body can make enough new bone. The bone starts to die and may break down.</p> <p>You can have osteonecrosis in one or several bones. It is most common in the upper leg. Other common sites are your upper arm and your knees, shoulders and ankles. The disease can affect men and women of any age, but it usually strikes in your thirties, forties or fifties. </p> <p>At first, you might not have any symptoms. As the disease gets worse, you will probably have joint pain that becomes more severe. You may not be able to bend or move the affected joint very well. </p> <p>No one is sure what causes the disease. Risk factors include :</p><ul> <li> Long-term steroid treatment</li> <li> Alcohol misuse</li> <li> Joint injuries</li> <li> Having certain diseases, including arthritis and cancer </li> </ul> <p>Doctors use imaging tests and other tests to diagnose osteonecrosis. Treatments include medicines, using crutches, limiting activities that put weight on the affected joints, electrical stimulation and surgery.</p> <p class="">NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0029445

cui

C0029445

Date created

05/02/2002

definition

Osteonecrosis is a disease caused by reduced blood flow to bones in the joints. In people with healthy bones, new bone is always replacing old bone. In osteonecrosis, the lack of blood causes the bone to break down faster than the body can make enough new bone. The bone starts to die and may break down.

You can have osteonecrosis in one or several bones. It is most common in the upper leg. Other common sites are your upper arm and your knees, shoulders and ankles. The disease can affect men and women of any age, but it usually strikes in your thirties, forties or fifties.

At first, you might not have any symptoms. As the disease gets worse, you will probably have joint pain that becomes more severe. You may not be able to bend or move the affected joint very well.

No one is sure what causes the disease. Risk factors include :

  • Long-term steroid treatment
  • Alcohol misuse
  • Joint injuries
  • Having certain diseases, including arthritis and cancer

Doctors use imaging tests and other tests to diagnose osteonecrosis. Treatments include medicines, using crutches, limiting activities that put weight on the affected joints, electrical stimulation and surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C3887513

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023234

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0085660

Inverse of SY

http://purl.bioontology.org/ontology/MEDLINEPLUS/C3887513

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0085660

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0029445

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0029445

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/osteonecrosis.html

MP PRIMARY INSTITUTE URL

National Institute of Arthritis and Musculoskeletal and Skin Diseases http://www.niams.nih.gov/

notation

C0029445

prefLabel

Osteonecrosis

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0005940

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456558

Scope Statement

Osteonecrosis (Avascular Necrosis) is marked by a loss of blood supply to the bones, causing bone to break down faster than the body make new bone. https://medlineplus.gov/osteonecrosis.html

tui

T046

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C1456595

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http://www.ebi.ac.uk/efo/EFO_0004259 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.bioontology.org/ontology/ICD10CM/M87 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI
http://purl.bioontology.org/ontology/ICD10CM/M87 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 LOOM
http://purl.bmicc.cn/ontology/ICD10CN/M87.9 《国际疾病分类》第10版中文版 / International Classification of Diseases, 10th Edition, China CUI
http://purl.obolibrary.org/obo/DOID_10159 BioAssay Ontology / 生物活性分析本体 LOOM
http://purl.obolibrary.org/obo/DOID_10159 Human Disease Ontology / 人类疾病本体 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/FB81 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM
http://purl.bmicc.cn/ontology/ICD10CN/M87 《国际疾病分类》第10版中文版 / International Classification of Diseases, 10th Edition, China CUI
http://purl.bioontology.org/ontology/ICD10CM/M87.9 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU012842 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU012842 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bioontology.org/ontology/MESH/D010020 Medical Subject Headings / 医学主题词表 CUI
http://purl.bioontology.org/ontology/MESH/D010020 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/ICD10/M87 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 CUI
http://purl.bioontology.org/ontology/ICD10/M87 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 LOOM
http://purl.obolibrary.org/obo/MONDO_0005380 Mondo Disease Ontology / Mondo疾病本体 LOOM
http://www.orpha.net/ORDO/Orphanet_399158 Orphanet Rare Disease Ontology / Orphanet罕见病本体 LOOM
http://purl.bioontology.org/ontology/ICD10/M87.9 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 CUI