| Preferred Name |
Osteoporosis |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3298 |
| ALT_DEFINITION |
Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years. A condition that is marked by a decrease in bone mass and density, causing bones to become fragile. A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. |
| code |
C3298 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186336 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 |
| Contributing_Source |
NICHD CTRP GDC PCDC |
| DEFINITION |
A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). |
| Display_Name |
Osteoporosis |
| FULL_SYN |
osteoporosis Osteoporosis |
| Is_Value_For_GDC_Property | |
| label |
Osteoporosis |
| Legacy Concept Name |
Osteoporosis |
| Maps_To |
Osteoporosis, unspecified Osteoporosis or Osteopenia |
| Preferred_Name |
Osteoporosis |
| prefixIRI |
Thesaurus:C3298 |
| prefLabel |
Osteoporosis |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C4014080 |
| subClassOf |