loading...| Preferred Name |
kuru |
| Synonyms |
kuru encephalopathy |
| Definitions |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
| ID |
http://purl.obolibrary.org/obo/MONDO_0006825 |
| closeMatch | |
| database_cross_reference |
MedDRA:10023497 SCTID:86188000 MESH:D007729 UMLS:C0022802 ICD9:046.0 DOID:648 GARD:0007617 Orphanet:454745 EFO:1001008 ICD10CM:A81.81 |
| definition |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
| disease arises from feature | |
| exactMatch |
http://purl.bioontology.org/ontology/ICD10CM/A81.81 http://identifiers.org/snomedct/86188000 http://linkedlifedata.com/resource/umls/id/C0022802 http://purl.obolibrary.org/obo/DOID_648 |
| has_exact_synonym |
kuru encephalopathy |
| id |
MONDO:0006825 |
| in_subset | |
| label |
kuru |
| notation |
MONDO:0006825 |
| prefLabel |
kuru |
| seeAlso | |
| treeView |
http://purl.obolibrary.org/obo/MONDO_0005429 |
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0005429 |