Medical Subject Headings / 医学主题词表

Last uploaded: September 7, 2023

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Preferred Name	Quinidine
Synonyms	Apo-Quinidine
Definitions	An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
ID	http://purl.bioontology.org/ontology/MESH/D011802
altLabel	Apo-Quinidine Adaquin Quinidex Apo Quinidine Cinchonan-9-ol, 6'-methoxy-, (9S)- Sulfate, Quinidine Quinora Quincardine Chinidin Quinidine Sulfate
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0034436 C1564018 C1564019 C1564020 C0034415 C1564021 C0034414
DC	1
definition	An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
DX	19660101
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	J13S2394HE ITX08688JL 0
isa	http://purl.bioontology.org/ontology/MESH/D000962 http://purl.bioontology.org/ontology/MESH/D065690 http://purl.bioontology.org/ontology/MESH/D004791 http://purl.bioontology.org/ontology/MESH/D000889 http://purl.bioontology.org/ontology/MESH/D018727 http://purl.bioontology.org/ontology/MESH/D000317 http://purl.bioontology.org/ontology/MESH/D061567
LT	TRD
Mapped from	http://purl.bioontology.org/ontology/MESH/C454102 http://purl.bioontology.org/ontology/MESH/C052071 http://purl.bioontology.org/ontology/MESH/C047144 http://purl.bioontology.org/ontology/MESH/C009764 http://purl.bioontology.org/ontology/MESH/C004561 http://purl.bioontology.org/ontology/MESH/C033457 http://purl.bioontology.org/ontology/MESH/C039166 http://purl.bioontology.org/ontology/MESH/C045112 http://purl.bioontology.org/ontology/MESH/C014486 http://purl.bioontology.org/ontology/MESH/C064337 http://purl.bioontology.org/ontology/MESH/C507057 http://purl.bioontology.org/ontology/MESH/C582850 http://purl.bioontology.org/ontology/MESH/C028170 http://purl.bioontology.org/ontology/MESH/C571402 http://purl.bioontology.org/ontology/MESH/C042206 http://purl.bioontology.org/ontology/MESH/C011064 http://purl.bioontology.org/ontology/MESH/C066172 http://purl.bioontology.org/ontology/MESH/C016713 http://purl.bioontology.org/ontology/MESH/C013569 http://purl.bioontology.org/ontology/MESH/C034410 http://purl.bioontology.org/ontology/MESH/C534592
MDA	19990101
MMR	20170524
MN	D03.605.687.637 D03.633.100.810.699 D03.132.206.636
notation	D011802
PA	D000962 D061567 D000889 D018727 D004791 D000317 D065690
prefLabel	Quinidine
RR	J13S2394HE 56-54-2 (Quinidine)
TERMUI	T616750 T034856 T034855 T034857 T616746 T616744 T616748 T034854
TH	FDA SRS (2014) USP (19XX) US UNK (19XX) BAN (19XX) CA AU
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D002930 http://purl.bioontology.org/ontology/MESH/D011812 http://purl.bioontology.org/ontology/MESH/D011804

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/LNC/MTHU060473	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/MTHU060473	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM
http://purl.bioontology.org/ontology/LNC/LP16271-6	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/LP16271-6	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	BioAssay Ontology / 生物活性分析本体	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	The Drug Ontology / 药物本体	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	Human Disease Ontology / 人类疾病本体	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	Experimental Factor Ontology / 实验性因素本体	LOOM
http://www.bioassayontology.org/bao#BAO_0000797	BioAssay Ontology / 生物活性分析本体	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C793	National Cancer Institute Thesaurus / 美国国家癌症研究所词典	LOOM
http://purl.bmicc.cn/ontology/ICD11CN/XM8AL5	《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China	LOOM
http://purl.bioontology.org/ontology/ATC/C01BA01	Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统	CUI
http://purl.bioontology.org/ontology/ATC/C01BA01	Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统	LOOM