Preferred Name

Fosphenytoin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65766

A5

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47543

CAS_Registry

93390-81-9

Chemical_Formula

C16H15N2O6P

code

C65766

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A water-soluble phosphate ester prodrug of phenytoin, a hydantoin derivative with anticonvulsant activity. Fosphenytoin is hydrolyzed to phenytoin by phosphatases. Phenytoin exerts its effect mainly by promoting sodium efflux and stabilizes neuronal membranes in the motor cortex. This leads to a suppression of excessive neuronal firing and limits the spread of seizure activity.

FDA_UNII_Code

B4SF212641

FULL_SYN

Fosphenytoin

FOSPHENYTOIN

label

Fosphenytoin

Legacy Concept Name

Fosphenytoin

Preferred_Name

Fosphenytoin

prefixIRI

Thesaurus:C65766

prefLabel

Fosphenytoin

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0244656

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C264

Delete Subject Author Type Created
No notes to display