loading...| Preferred Name |
carcinoma |
| Synonyms |
malignant epithelial neoplasm epithelioma malignant malignant epithelioma epithelioma epithelial carcinoma Other carcinoma malignant epithelial tumor carcinoma, malignant carcinoma |
| Definitions |
A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. |
| ID |
http://www.ebi.ac.uk/efo/EFO_0000313 |
| closeMatch |
http://identifiers.org/snomedct/189549006 http://linkedlifedata.com/resource/umls/id/C0553707 http://identifiers.org/snomedct/269513004 http://identifiers.org/snomedct/189546004 http://identifiers.org/snomedct/189559007 http://identifiers.org/snomedct/71298006 http://identifiers.org/snomedct/134207000 http://linkedlifedata.com/resource/umls/id/C1368683 http://identifiers.org/snomedct/188083002 |
| database_cross_reference |
UMLS:C0007097 ICDO:8011/3 DOID:305 NCIT:C2916 CSP:2000-1867 MESH:D002277 SCTID:722688002 ICDO:8010/3 MONDO:0004993 EFO:0000313 |
| definition |
A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. |
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0007097 http://purl.obolibrary.org/obo/DOID_305 http://identifiers.org/snomedct/722688002 |
| gwas_trait |
true |
| has_broad_synonym |
epithelioma |
| has_exact_synonym |
malignant epithelial neoplasm epithelioma malignant malignant epithelioma epithelioma epithelial carcinoma Other carcinoma malignant epithelial tumor carcinoma, malignant carcinoma |
| id |
EFO:0000313 |
| label |
carcinoma |
| notation |
EFO:0000313 |
| prefLabel |
carcinoma |
| subClassOf |