Preferred Name

CD274 wt Allele

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96023

code

C96023

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

Human CD274 wild-type allele is located in the vicinity of 9p24 and is approximately 20 kb in length. This allele, which encodes programmed cell death 1 ligand 1 protein, plays a role in the regulation of T cell stimulation and proliferation.

DesignNote

Fusion of the CD274 gene and the CITTA gene may be associated with lymphoid cancers. (Nature 2011; doi:10.1038/nature09754.)

Display_Name

CD274 wt Allele

EntrezGene_ID

29126

FULL_SYN

B7H1

PD-L1

Programmed Cell Death 1 Ligand 1 Gene

B7-H

PDL1

PDCD1LG1

MGC142296

MGC142294

PDCD1L1

CD274 Antigen Gene

CD274 Molecule wt Allele

CD274 wt Allele

GenBank_Accession_Number

AF177937

label

CD274 wt Allele

OMIM_Number

605402

Preferred_Name

CD274 wt Allele

prefixIRI

Thesaurus:C96023

prefLabel

CD274 wt Allele

Semantic_Type

Gene or Genome

UMLS_CUI

C3272500

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96022

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