loading...| Preferred Name |
G protein-coupled receptor signaling pathway |
| Synonyms |
G protein coupled receptor protein signaling pathway GPCR signaling pathway dimeric G-protein coupled receptor signaling pathway G-protein coupled receptor signaling pathway via GPCR dimer G-protein coupled receptor signalling pathway G-protein coupled receptor protein signaling pathway G protein coupled receptor protein signalling pathway dimeric G-protein coupled receptor signalling pathway GPCR signalling pathway G-protein-coupled receptor protein signalling pathway G-protein coupled receptor protein signal transduction |
| Definitions |
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| ID |
http://purl.obolibrary.org/obo/GO_0007186 |
| definition |
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| has_alternative_id |
GO:0038042 |
| has_exact_synonym |
G protein coupled receptor protein signaling pathway GPCR signaling pathway G-protein coupled receptor signalling pathway G-protein coupled receptor protein signaling pathway G protein coupled receptor protein signalling pathway GPCR signalling pathway G-protein-coupled receptor protein signalling pathway G-protein coupled receptor protein signal transduction |
| has_narrow_synonym |
dimeric G-protein coupled receptor signaling pathway G-protein coupled receptor signaling pathway via GPCR dimer dimeric G-protein coupled receptor signalling pathway |
| has_obo_namespace |
biological_process |
| id |
GO:0007186 |
| in_subset | |
| label |
G protein-coupled receptor signaling pathway |
| notation |
GO:0007186 |
| prefLabel |
G protein-coupled receptor signaling pathway |
| treeView | |
| subClassOf |