loading...| Preferred Name |
Acne |
| Synonyms |
Breaking out Acne |
| Definitions |
Acne can be a consequence of increased sebum production as a result of increased testosterone production (in males and females) during puberty. Blockage of hair follicles canresult from accumulating keratin and sebum, resulting in plug formation called microcomedone, which can enlarge just beneath the surface of the skin in the pore itself. It may become visible as a closed comedone (whitehead), a firm white papule. Further enlargement leads to an open comedone (blackhead). The comedones are not themselves inflammatory. Proprionibacterium acnes can induce inflammation, leding to an inflammed, red papule. A skin condition in which there is an increase in sebum secretion by the pilosebaceous apparatus associated with open comedones (blackheads), closed comedones (whiteheads), and pustular nodules (papules, pustules, and cysts). |
| ID |
http://purl.obolibrary.org/obo/HP_0001061 |
| comment |
Acne can be a consequence of increased sebum production as a result of increased testosterone production (in males and females) during puberty. Blockage of hair follicles canresult from accumulating keratin and sebum, resulting in plug formation called microcomedone, which can enlarge just beneath the surface of the skin in the pore itself. It may become visible as a closed comedone (whitehead), a firm white papule. Further enlargement leads to an open comedone (blackhead). The comedones are not themselves inflammatory. Proprionibacterium acnes can induce inflammation, leding to an inflammed, red papule. |
| database_cross_reference |
SNOMEDCT_US:11381005 UMLS:C0702166 MEDDRA:10000496 |
| definition |
A skin condition in which there is an increase in sebum secretion by the pilosebaceous apparatus associated with open comedones (blackheads), closed comedones (whiteheads), and pustular nodules (papules, pustules, and cysts). |
| has_alternative_id |
HP:0005596 |
| has_broad_synonym |
Breaking out |
| has_exact_synonym |
Acne |
| has_obo_namespace |
human_phenotype |
| id |
HP:0001061 |
| in_subset | |
| label |
Acne |
| notation |
HP:0001061 |
| prefLabel |
Acne |
| treeView | |
| subClassOf |