loading...| Preferred Name |
amifostine |
| Synonyms |
amifostine amifostinum Ethyol amifostina S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate Amifostine |
| Definitions |
An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. |
| ID |
http://purl.obolibrary.org/obo/CHEBI_2636 |
| charge |
0 |
| database_cross_reference |
PMID:16465691 PMID:22402174 HMDB:HMDB0015274 PMID:8683243 PMID:12005544 PMID:23092832 PMID:20334641 PMID:21646919 KEGG:C06819 CAS:20537-88-6 PMID:10553165 Drug_Central:156 PMID:22643562 LINCS:LSM-4721 PMID:18549666 Beilstein:2088122 PMID:14980067 PMID:22989457 PMID:12751907 PMID:22878481 PMID:12499421 PMID:21347716 Patent:US3892824 Reaxys:2088122 PMID:23052919 PMID:22885239 PMID:22456378 PMID:8612469 PMID:22844290 PMID:17602063 PMID:22440042 PMID:11201306 PMID:15698860 PMID:12433814 PMID:19712749 PMID:15875769 PMID:18072151 PMID:22496587 PMID:10942928 PMID:11013273 Wikipedia:Amifostine PMID:15380592 PMID:23040218 DrugBank:DB01143 PMID:22267539 PMID:11984063 PMID:12561384 PMID:23401928 |
| definition |
An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. |
| formula |
C5H15N2O3PS |
| has functional parent | |
| has role |
http://purl.obolibrary.org/obo/CHEBI_22586 |
| has_exact_synonym |
S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate Amifostine |
| has_obo_namespace |
chebi_ontology |
| has_related_synonym |
amifostine amifostinum Ethyol amifostina |
| id |
CHEBI:2636 |
| in_subset | |
| inchi |
InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10) |
| inchikey |
JKOQGQFVAUAYPM-UHFFFAOYSA-N |
| label |
amifostine |
| mass |
214.22404 |
| monoisotopicmass |
214.05410 |
| notation |
CHEBI:2636 |
| prefLabel |
amifostine |
| smiles |
NCCCNCCSP(O)(O)=O |
| treeView | |
| subClassOf |