loading...| Preferred Name |
OBESITY |
| Synonyms |
LEANNESS |
| ID |
http://purl.bioontology.org/ontology/OMIM/601665 |
| altLabel |
LEANNESS |
| cui |
C0039870 C0028754 |
| Gene Locus |
3p26-p25 |
| Gene Symbol |
GHRL |
| Has manifestation | |
| MIMTYPEMEANING |
Phenotype description, molecular basis known. |
| notation |
601665 |
| OMIM Entry Type |
3 |
| OMIM MimType Value |
pound |
| prefLabel |
OBESITY |
| Scope Statement |
Caused by mutation in the nuclear receptor subfamily 0, group B, member 2 gene (NR0B2, 604630.0001) [MOLECULAR BASIS] Caused by mutation in the gamma peroxisome proliferator activated receptor gene (PPARG, 601487.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the cocaine- and amphetamine-regulated transcript prepropeptide (CARTPT, 602606.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the beta-3-adrenergic receptor gene (ADRB3, 109691.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the uncoupling protein-1 gene (UCP1, 113730.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the ghrelin gene (GHRL, 605353.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the homolog of the mouse agouti gene (AGRP, 602311.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene (ENPP1, 173335.0001) [MOLECULAR BASIS] See also leptin deficiency (614962) and summary information in BMIQ1 (606641) [MISCELLANEOUS] Susceptibility conferred by mutation in the beta-2-adrenergic receptor gene (ADRB2, 109690.0002) [MOLECULAR BASIS] Caused by mutation in the melanocortin-4 receptor gene (MC4R, 155541.0001) [MOLECULAR BASIS] Susceptibility conferred by mutation in the proopiomelanocortin gene (POMC, 176830.0001) [MOLECULAR BASIS] Variable phenotypic severity [MISCELLANEOUS] Susceptibility conferred by mutation in the uncoupling protein-2 gene (UCP2, 601693.0001) [MOLECULAR BASIS] Caused by mutation in the uncoupling protein-3 gene (UCP3, 602044.0001) [MOLECULAR BASIS] |
| tui |
T033 T047 |