| Preferred Name |
Troponin T |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38041 |
| code |
C38041 |
| DEFINITION |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
| FULL_SYN |
Troponin T TNNT |
| label |
Troponin T |
| Legacy Concept Name |
Troponin_T |
| Preferred_Name |
Troponin T |
| prefixIRI |
Thesaurus:C38041 |
| prefLabel |
Troponin T |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| UMLS_CUI |
C0077404 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/D020107 | Medical Subject Headings / 医学主题词表 | LOOM | |
| http://purl.org/sig/ont/fma/fma67900 | Foundational Model of Anatomy / 解剖学基础模型本体 | LOOM |