Preferred Name

Troponin T

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38041

code

C38041

DEFINITION

Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury.

FULL_SYN

Troponin T

TNNT

label

Troponin T

Legacy Concept Name

Troponin_T

Preferred_Name

Troponin T

prefixIRI

Thesaurus:C38041

prefLabel

Troponin T

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0077404

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16492

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http://purl.bioontology.org/ontology/MESH/D020107 Medical Subject Headings / 医学主题词表 LOOM
http://purl.org/sig/ont/fma/fma67900 Foundational Model of Anatomy / 解剖学基础模型本体 LOOM