loading...| Preferred Name |
spleen |
| Synonyms |
lien |
| Definitions |
The organ that functions to filter blood and to store red corpuscles and platelets. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
| database_cross_reference |
galen:Spleen VHOG:0000120 GAID:1289 Wikipedia:Spleen NCIT:C12432 MA:0000141 MESH:D013154 EV:0100055 MIAA:0000085 UMLS:C0037993 CALOHA:TS-0956 ZFA:0000436 AAO:0010395 EFO:0000869 MAT:0000085 SCTID:181279003 TAO:0000436 BTO:0001281 XAO:0000328 FMA:7196 EMAPA:18767 |
| definition |
The organ that functions to filter blood and to store red corpuscles and platelets. |
| depicted by |
https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg |
| develops_from | |
| external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
| function_notes |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
| has related synonym |
lien |
| has_obo_namespace |
uberon |
| has_relational_adjective |
splenic lienal |
| homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
| id |
UBERON:0002106 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#pheno_slim |
| label |
spleen |
| located in | |
| notation |
UBERON:0002106 |
| only in taxon | |
| part_of |
http://purl.obolibrary.org/obo/UBERON_0000916 http://purl.obolibrary.org/obo/UBERON_0002405 |
| prefLabel |
spleen |
| present_in_taxon | |
| taxon_notes |
Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron |
| treeView |
http://purl.obolibrary.org/obo/UBERON_0000916 http://purl.obolibrary.org/obo/UBERON_0006293 http://purl.obolibrary.org/obo/UBERON_0002405 |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0005057 http://purl.obolibrary.org/obo/UBERON_0004177 |
| disjointWith |