Preferred Name |
heart |
Synonyms |
chambered heart branchial heart cardium Herz@de vertebrate heart |
Definitions |
A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 |
ID |
http://purl.obolibrary.org/obo/UBERON_0000948 |
comment |
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 |
axiom_lost_from_external_ontology |
relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO] |
database_cross_reference |
XAO:0000064 EHDAA2:0000738 OpenCyc:Mx4rvVjvDpwpEbGdrcN5Y29ycA galen:Heart MAT:0000036 EFO:0000815 EHDAA:420 MA:0000072 TAO:0000114 GAID:174 UMLS:C0018787 EV:0100018 BILA:0000020 NCIT:C12727 EMAPA:16105 AAO:0010210 MIAA:0000036 CALOHA:TS-0445 FMA:7088 VHOG:0000276 BTO:0000562 MESH:D006321 ZFA:0000114 http://linkedlifedata.com/resource/umls/id/C0018787 |
editor preferred label |
heart |
external_definition |
Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO] Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO] |
has exact synonym |
chambered heart vertebrate heart |
has_narrow_synonym |
branchial heart |
has_obo_namespace |
uberon |
has_related_synonym |
cardium Herz@de |
has_relational_adjective |
cardiac |
homology_notes |
As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG] |
id |
UBERON:0000948 |
imported from | |
in subset |
http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#organ_slim http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim |
label |
heart |
notation |
UBERON:0000948 |
prefLabel |
heart |
textual definition |
A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. |
subClassOf |
http://purl.obolibrary.org/obo/UBERON_0003103 http://purl.obolibrary.org/obo/UBERON_0005181 http://purl.obolibrary.org/obo/UBERON_0010314 |